2HC5ME is a 'noobspeak' for 2HC4ME, which stands for Two-Hour Compo For My Entry. Other interpretations include:
- Too Hardcore For Me
- Too Hard Crushed For My Ears
- Two Heavy Circuits For Mega Electricity
- Two Helicopters Crash For Massive Explosion
- Two Huggable Cats For My Enjoyment
- Twin Hydro-Casting For Metal Editing
- Two Helpful Couriers For Map Exploring
- Two Hellkite Conjourers, Four Mammoth Eagles